Biomaterialien — Nachbildung der Stammzellnische in Bioreaktoren

Abstract The generation of high-quality human pluripotent stem cells and their derivatives requires growth surfaces imitating the natural micro-environment. Stiff plastic with protein coatings are not an optimal cell niche adjustable needed to meet cell-specific requirements. Alginate hydrogels versatile biomaterials in processes since they can be integrated all fundament workflows only as planar surface but also microcarrier cultures suspension bioreactors.